PN 2: Project Overview

PN 2-1A Data-integrated Modeling to Provide Novel Solutions for Individualizing Cancer Therapy and Predicting Treatment Success
PN 2-1 (II) Development of a data-integrated ODE and agent-based simulation framework that captures and predicts responsiveness to targeted cancer therapeutics
PN 2-1B Data-integrated Modeling to Provide Novel Solutions for Individualizing Cancer Therapy and Predicting Treatment Success
PN 2-2A Data and Model Driven Multiscale Simulation of Tumor Growth in Liver Cell, Tissue and Organ
PN 2-2 (II) Data-enhanced prediction of organ-specific tumor growth in the liver - a hybrid knowledge and data-driven approach
PN 2-2B Data-Integrated Simulation of Tumour Growth and Regression in Brain Tissue
PN 2-3A Investigating sensorimotor interaction through selective sensory perturbations
PN 2-3 (II) Separating motor and neural effects of somatosensory perturbations
PN 2-3B Enhanced proprioceptor dynamics to predict sensorimotor interaction of a biophysical hand-arm-model
PN 2-4A Machine learning-based decomposition of the activity of individual motor units from synthetic and experimental data
PN 2-4B Machine learning-based decomposition of the activity of individual motor units from synthetic and experimental data
PN 2-5 Molecular Dynamics Simulations of the Substrate Recognition of Protein Lysine Methyltransferases
PN 2-6 Seamlesss data flow by EnzymeML, an SBML-based exchange format for the integration of enzymatic reaction data
PN 2-6 (II) Software-driven RDM (sdRDM), a generic and extensible bottom-up research data management concept and its application in biocatalysis and beyond
PN 2-7 Data-Integrated Training of Surrogate Models for Uncertainty Quantification and Diagnostics of Complex Biological Systems Models
PN 2-8 Modelling of architectural-informed and activation-driven contractions of the human M. tibialis anterior
PN 2-9 Methodology for the calibration and analysis of stochastic models for heterogeneous intracellular processes with applications in cancer development

Project Network Coordinators

This image shows Nicole Radde

Nicole Radde

Prof. Dr. rer. nat.

Mathematical Modeling and Simulation of Cellular Systems

[Photo: SimTech/Max Kovalenko]

This image shows Oliver Röhrle

Oliver Röhrle

Prof.

Continuum Biomechanics and Mechanobiology

[Photo: SimTech/Max Kovalenko]

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